Capparis spinosa L

Fiorito, Serena, Epifano, Francesco, Preziuso, Francesca, Taddeo, Vito Alessandro & Genovese, Salvatore, 2018, Selenylated plant polysaccharides: A survey of their chemical and pharmacological properties, Phytochemistry 153, pp. 1-10 : 5

5.7.1. Capparis spinosa L

Capparis spinosa is a well characterized and worldwide used food plant with several beneficial effects for human health, part of which attributable to its polysaccharide fraction ( Mazarei et al., 2017). In 2012 Ji and coworkers synthesized a library of 17 samples of Se-Ps featured by a Se content in the range 2.44–5.54 mg /g. The polymer with the highest content of Se was assayed as an in vitro growth inhibitory agent against SGC-7901 (human gastric carcinoma) cell line by the MTT test in concentrations ranging from 50 μg/mL to 400 μg/mL and over a period of 72 h. A dose- and time-dependent effect was recorded: after 72 h and at the highest dose applied the growth inhibitory effect reached 70% while the one of the native polymer was only nearly 20%. The value obtained for the Se-P was comparable to the one revealed at the same time by doxorubicin (32 μg/mL) used as the reference.