Skimmia repens, Nakai, Nakai

Epifano, Francesco, Fiorito, Serena, Genovese, Salvatore, Granica, Sebastian, Vitalini, Sara & Zidorn, Christian, 2015, Phytochemistry of the genus Skimmia (Rutaceae), Phytochemistry 115 (1), pp. 27-43 : 35

3.8. S. repens

S. repens is a shrub, native to the Himalyan region, often cultivated for decorative purposes. ( Ohta and Miyazaki, 1956) The first phytochemical study about S. repens dates back to 1930 when in two distinct papers Asahina et al. 1930 reported the isolation of the alkaloids skimmianine 13 and dictamnine 12 from extracts of the whole plant. The structure of the latter compound was unambiguously confirmed by chemical synthesis in 1956 and 1957 by Sato and Ohta who obtained dictamnine and its direct precursor dictamnal. In 1938 Späth and Neufeld (1938a) turned their attention to the coumarin profile of the ether extract of the title plant and described the isolation and structural determination of seselin 65. About twenty years later Ohta and Miyazaki (1956) described the fatty acid profile of the apolar extract of fruits of S. repens and found that palmitic and stearic acids were the main components with minor percentages of linolenic, linoleic, and oleic acids listed in increasing order. S. repens so far yielded only few secondary metabolites and more detailed future investigations, both phytochemical and pharmacological, are destined to reveal new activities and additional secondary metabolites for this species.